As the aroma of bubbling cheese wafts through the air, I can’t help but reminisce about family gatherings centered around a warm dish of Missouri Casserole. This delightful comfort food weaves together tender pasta, seasoned ground beef, and a vibrant blend of tomatoes, creating layers of flavor that warm the soul. It’s the kind of dish that transforms dinner into a cozy experience, perfect for busy weeknights or joyful celebrations. And the best part? It’s incredibly easy to throw together, making it an ideal solution for those days when cooking feels like a daunting task. Trust me, once you serve this hearty pasta bake, everyone at your table will be craving seconds. Ready to dig in? Let’s dive into the recipe!
Why is Missouri Casserole a Must-Try?
Comforting Nostalgia: This dish brings back memories of family dinners where everyone gathers around the table, savoring each blissful bite.
Easy Assembly: With straightforward steps, you can whip up this delightful casserole in no time, making it perfect for even the busiest evenings.
Hearty Ingredients: Packed with ground beef and melty cheese, the flavors meld beautifully, creating a satisfying meal that leaves everyone feeling full and happy.
Versatile Bonus: Feel free to customize your casserole by adding your favorite veggies or even swapping ground beef for lentils to cater to different dietary needs.
Crowd-Pleasing Delight: Whether it's a family gathering or a casual dinner party, this dish is sure to impress and keep everyone asking for the recipe!
Why not complete your meal with a refreshing salad or some buttery garlic bread? You’ll have a feast that’ll be remembered!
Missouri Casserole Ingredients
For the Beef Mixture
• Ground Beef – Provides essential protein and a savory base for the casserole; substitute with ground turkey for a lighter option.
• Onion – Adds aromatic flavor and sweetness; red or yellow onions can be used interchangeably.
• Bell Peppers – Contributes texture and sweetness; choose red or yellow for a vibrant taste.
• Garlic – Enhances the overall flavor with its robust aroma; fresh is best; use garlic powder if needed.
For the Sauce
• Crushed Tomatoes (28 oz) – Forms the sauce base, adding moisture and acidity; diced tomatoes can create a chunkier texture.
• Tomato Paste – Intensifies tomato flavor and thickens the sauce.
For the Pasta and Cheese
• Egg Noodles (12 oz) – Provides the casserole's hearty body; swap with rotini for a twist.
• Shredded Cheddar Cheese (1.5 cups) – Adds creaminess and flavor; a mix of sharp cheddar and Monterey Jack works wonders.
• Shredded Mozzarella Cheese (1.5 cups) – Offers that gooey melt; consider adding provolone for a richer taste.
For Seasoning and Garnish
• Salt (1 tsp) – Enhances all flavors; adjust according to your taste preference.
• Black Pepper (½ tsp) – Adds seasoning with a mild kick.
• Fresh Parsley (for garnish) – Brings a fresh finish; omit if you don’t have any on hand.
Gather these wonderful ingredients, and you’ll be one step closer to enjoying a delicious Missouri Casserole!
Step‑by‑Step Instructions for Missouri Casserole
Step 1: Brown the Beef
In a large skillet, heat over medium heat, then add the ground beef. Break it apart using a spatula as it cooks, browning for about 7-10 minutes until fully cooked and no longer pink. Drain any excess fat, leaving the savory juices to enhance the flavor of your Missouri Casserole.
Step 2: Sauté the Vegetables
Add the chopped onion, bell peppers, and minced garlic to the skillet with the browned beef. Sauté the mixture for 5-7 minutes, stirring occasionally, until the vegetables are tender and fragrant. This step will infuse the casserole with irresistible aromas, setting a delightful tone for your meal.
Step 3: Prepare the Sauce
Stir in the crushed tomatoes and tomato paste, along with the salt and black pepper. Allow the sauce to simmer on low heat for about 10 minutes, stirring occasionally. You’ll notice the mixture thickening and developing a rich, robust flavor, perfect for coating the pasta and ground beef in your Missouri Casserole.
Step 4: Cook the Pasta
In a large pot, bring salted water to a rolling boil. Add the egg noodles and cook according to package instructions until al dente, usually around 7-9 minutes. Drain the pasta in a colander, making sure to shake off excess water, and set aside while you layer the casserole.
Step 5: Layer the Casserole
Preheat your oven to 375°F (190°C). Grease a 9x13 inch baking dish. Begin layering by spreading half of the meat sauce at the bottom, followed by half of the cooked pasta, and half of the shredded cheddar and mozzarella cheese. Repeat the layers, finishing with a generous topping of cheese to create that golden, bubbly finish of the Missouri Casserole.
Step 6: Bake the Casserole
Cover the layered casserole with aluminum foil and bake in the preheated oven for 20 minutes. After this time, remove the foil and continue to bake for an additional 10-15 minutes until the cheese is golden and bubbly. Keep an eye on it as it bakes, allowing the rich flavors to meld beautifully.
Step 7: Rest and Serve
Once baked, let the Missouri Casserole rest for 5-10 minutes before slicing. This resting period helps maintain the structure of the layers, making it easier to serve. Before serving, garnish with fresh parsley for a burst of color and flavor, then enjoy the comforting goodness with your loved ones!
What to Serve with Missouri Casserole
The perfect meal is just a few delicious accompaniments away from transforming your cozy casserole night into a full feast!
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Crisp Green Salad: A refreshing side that adds crunch and balances the richness of the casserole, drizzled with a zesty vinaigrette.
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Garlic Bread Sticks: Buttery and warm, these mouthwatering sticks are perfect for sopping up every bit of savory sauce, enhancing the comforting experience.
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Steamed Broccoli: The vibrant green of steamed broccoli not only adds color to your plate but also brings a nutritional boost and a delightful texture contrast.
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Roasted Vegetables: A medley of seasonal veggies brings sweetness and earthiness, complementing the savory layers of your Missouri Casserole wonderfully.
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Creamy Coleslaw: This crunchy, tangy dish adds a refreshing crunch and a hint of sweetness, creating a delightful contrast with the rich flavors of the casserole.
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Homemade Applesauce: Ideal for adding a sweet touch, this side offers a comforting finish to the meal, especially loved by families with children. Enjoy this combination for a heartwarming dinner experience!
How to Store and Freeze Missouri Casserole
Fridge: Store leftovers in an airtight container for up to 3 days to maintain freshness and flavor. Reheat in the microwave or oven until heated through.
Freezer: Missouri Casserole freezes well! Wrap it tightly in plastic wrap and aluminum foil, then freeze for up to 3 months. Thaw in the fridge overnight before baking.
Reheating: For the best results, reheat in the oven at 350°F (175°C) until warmed and cheese is melty, about 20-25 minutes. Cover with foil to prevent drying out.
Make-Ahead: Prepare the casserole a day in advance and refrigerate before baking. This helps the flavors meld beautifully; just add 5-10 minutes to baking time if cold.
Missouri Casserole: Endless Customization Options
Feel free to explore delightful twists that make this comforting dish uniquely yours, creating an aromatic feast for your loved ones.
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Ground Beef Alternate: Substitute ground beef with ground turkey or plant-based meat for a lighter, yet equally hearty option. This switch maintains the dish's structure while being a bit kinder on the waistline.
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Vegetable Boost: Toss in chopped spinach, zucchini, or sautéed mushrooms for extra nutrition. These colorful additions will brighten your casserole, bringing an array of flavors and textures to each bite.
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Different Pasta Shape: Instead of egg noodles, try using rotini or shells for a fun twist on texture. Each pasta shape holds the sauce differently, creating a new experience with every serving.
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Kick Up the Heat: For spice lovers, sprinkle red pepper flakes or jalapeños into the meat mixture. A little added heat can elevate the flavors wonderfully, igniting excitement for those who crave a bolder flavor.
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Cheese Variety: Experiment with a blend of cheeses like gouda or pepper jack for an unexpected twist. Their unique flavors will melt beautifully and make your casserole truly memorable.
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Creamy Layer: Mix in a dollop of sour cream or cream cheese with the cheese layers for a rich, creamy finish. This addition not only enhances creaminess but adds a tangy depth that's utterly delicious.
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Herb Infusion: Add fresh herbs like basil or oregano into the meat sauce for a fresh pop of flavor. The fragrant aroma will fill your kitchen, enticing everyone to come to the table.
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Nut-Free Option: Omit cheese and use a plant-based cheese alternative for a dairy-free approach, catering to different dietary preferences. It’s a thoughtful swap that maintains the integrity of the dish while accommodating various needs.
Each of these variations offers a fresh take on the traditional Missouri Casserole, ensuring that your family never tires of this satisfying classic. For a complete meal, consider complementing it with a crisp salad or some warm, buttery garlic bread for that full comfort experience!
Expert Tips for Missouri Casserole
• Fresh Cheese First: Use freshly shredded cheese rather than pre-packaged for the best melt and flavor in your Missouri Casserole.
• Don’t Overbake: Keep an eye on your casserole to prevent overbaking; the goal is golden, bubbly cheese, not burnt edges!
• Rest Before Serving: Allow the casserole to sit for 5-10 minutes after baking to help maintain the layered structure; this makes serving much easier.
• Customize Wisely: Feel free to swap ground beef with turkey or lentils, but adjust cooking times accordingly to prevent drying out.
• Add Extra Veggies: Incorporate your favorite chopped vegetables into the mix to enhance flavor and nutrition; just ensure not to overload the layers!
Make Ahead Options
Missouri Casserole is a fantastic choice for meal prep enthusiasts! You can assemble the entire casserole up to 24 hours in advance by following the layering instructions and then covering it tightly with plastic wrap. To maintain quality, make sure to refrigerate it to prevent the noodles from becoming mushy. When you're ready to serve, simply preheat your oven to 375°F (190°C) and bake for about 30-35 minutes, adding an extra 5-10 minutes if it's been refrigerated. This way, you'll have a delightful and satisfying meal with minimal effort on busy weeknights, ensuring your family enjoys every delicious bite!
Missouri Casserole Recipe FAQs
What kind of ground beef should I use for Missouri Casserole?
I recommend using lean ground beef for a healthier option, but if you'd like to reduce the fat content further, ground turkey works beautifully too. If you're cooking for vegetarians, consider using lentils or plant-based meat alternatives!
How long can I store leftovers of Missouri Casserole?
Leftovers can be stored in an airtight container in the fridge for up to 3 days. To keep it fresh, make sure it cools down before sealing it. When you're ready to enjoy it again, just reheat in the microwave or oven until warmed through.
Can I freeze Missouri Casserole?
Absolutely! Wrap your cooled casserole tightly in plastic wrap and aluminum foil, then freeze for up to 3 months. When you’re ready to bake it, thaw it in the fridge overnight and bake it as per the recipe instructions, adding an additional 5-10 minutes if it’s been refrigerated.
How can I ensure my casserole doesn’t get dry when reheating?
To avoid dryness, reheat your Missouri Casserole in the oven at 350°F (175°C) covered with foil for about 20-25 minutes. This method allows it to warm evenly while keeping the cheese nice and melty. If you notice it needs extra moisture, sprinkle a little water over the top before covering with foil.
What should I do if my casserole is too watery?
If you’ve found your casserole is watery, there are a couple of things you can try: First, let it simmer longer during the sauce preparation to reduce moisture. If it's baked and still too watery, allow it to sit for a bit before serving; it will absorb some liquid as it cools. Adding more cheese on top can also provide a nice texture!
How can I make Missouri Casserole suitable for a specific dietary need?
You have plenty of options! Swap ground beef for lean turkey or lentils for a vegetarian option. For gluten-free diets, use gluten-free pasta and ensure that your sauces are gluten-free. You can also enrich the casserole by adding chopped spinach or zucchini to sneak in extra veggies!

Delicious Missouri Casserole for Ultimate Comfort Food Nights
Ingredients
Equipment
Method
- Brown the beef by heating a skillet over medium heat. Add the ground beef and brown for about 7-10 minutes until fully cooked. Drain excess fat.
- Sauté the chopped onion, bell peppers, and minced garlic in the same skillet for 5-7 minutes until tender.
- Prepare the sauce by stirring in crushed tomatoes, tomato paste, salt, and black pepper. Simmer on low for about 10 minutes.
- Cook the egg noodles in salted water according to package instructions until al dente, then drain.
- Preheat the oven to 375°F (190°C). Layer half of the meat sauce, half of the cooked pasta, and half of the cheeses in a greased baking dish. Repeat the layers.
- Cover with foil and bake for 20 minutes. Remove foil and bake for an additional 10-15 minutes until cheese is golden.
- Let the casserole rest for 5-10 minutes before slicing. Garnish with fresh parsley before serving.
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